Sarcoidosis and primary systemic vasculitis

Primary systemic vasculitis: clinical features and mortality.

BACKGROUND Wegener's granulomatosis (WG), Churg Strauss syndrome (CSS) and microscopic polyangiitis (MPA) are primary systemic vasculitides (PSV), the clinical features of which have been described from tertiary centres. AIM To provide the first clinical description of MPA from a general hospital and compare clinical features with WG and CSS. DESIGN Retrospective analysis of patient records...

Studies on the Epidemiology and Outcome of Primary Systemic Vasculitis

Systemic vasculitis.

The systemic vasculitides are characterized by inflammation of blood vessel walls. Vessels of any type, in any organ can be affected, resulting in a broad spectrum of signs and symptoms. The heterogenous nature of vasculitides presents a diagnostic challenge. The American College of Rheumatology classification criteria and the Chapel Hill Consensus Conference nomenclature are the most widely us...

Pulmonary hypertension and granulomatous vasculitis in sarcoidosis.

PURPOSE OF REVIEW To examine the recent advancements of the epidemiology, pathophysiology, clinical characteristics, radiographic studies, diagnostic modalities, treatment, and prognosis of pulmonary hypertension in sarcoidosis. RECENT FINDINGS A large retrospective study found 73.8% of patients with sarcoidosis listed for transplant had pulmonary hypertension. Several other studies found pul...

Biologic therapy in primary systemic vasculitis of the young.

OBJECTIVES To describe the biologic treatment regimens and report the efficacy and safety of biologic therapies in a multicentre series of children with primary systemic vasculitis (PSV). METHODS This was a retrospective descriptive case series of children with PSV treated with biologic therapy between February 2002 and November 2007. Primary retrospective outcome assessment measures were: da...